SHC1 and lung carcinoma: Furthermore, high expression of SHC1 was also associated with worse OS in stages 1 and 2 but not stage 3 lung cancer patients (OS HR = 1.86, logrank P < 0.01; OS HR = 1.7, logrank P = 0.0041; OS HR = 0.94, logrank P = 0.8145).