Regarding AP-2 transcription factors in the mammary gland and breast cancer, most studies have focused on TFAP2A/AP-2α and TFAP2C/AP-2γ (Friedrichs et al. 2005; Gee et al. 2009; Orso et al. 2004; Pellikainen et al. 2002; Shiu et al. 2014; Turner et al. 1998; Williams et al. 2009). The gene discussed is TFAP2A; the disease is breast cancer.