However, various prognostic BC gene expression signatures, such as the 496 intrinsic gene set, include TFAP2B as a classifier gene (Guedj et al. 2012; Hu et al. 2006; Korkola et al. 2003; Perou et al. 2000; Weigelt et al. 2010). The gene discussed is TFAP2B; the disease is breast cancer.