CD14 and cardiac arrest: Our main findings were (1) a significant decrease in the proportion of nonclassical monocytes during early PCAS, (2) a significant upregulation of CD14, which correlated with the time to ROSC, (3) a significant decrease in the expression of mHLA-DR, which was the result of downregulation on classical monocytes and which significantly correlated with the extent of post-cardiac arrest shock, and (4) an inhomogeneous expression of HLA-DR on intermediate and nonclassical monocytes within the CPR group, with patients having a worse prognosis or outcome showing lower HLA-DR levels on these cells.