When ADC vs. SCC label-free proteome differences were compared in this subset of 10 samples, over 30 proteins were significantly upregulated in ADC vs. SCC, among which NSCLC-relevant proteins such as NAPSA and NQO1, another member of the Keap1-Nrf2 pathway, were represented (Supplementary Fig. 2B). This evidence concerns the gene NQO1 and AIDS dementia complex.