While our study focused on oral cancer and comprehensively investigated the function of LCK in an oral squamous cell carcinoma-derived cell line, it is important to note that LCK has previously been shown to be aberrantly expressed in colon, prostate, and small cell lung carcinoma cells with a trend towards preferential expression in metastatic cancers [56, 57]. Here, LCK is linked to lip and oral cavity carcinoma.