The top ten most enriched pathways included “hematopoietic cell lineage”, “adhesion molecules cams”, “vascular smooth muscle contraction”, “systemic lupus erythematosus”, “chemokine signaling pathway”, “t cell receptor signaling pathway”, “cytokine cytokine receptor interaction”, “calcium signaling pathway”, “neuroactive ligand receptor interaction” and “leukocyte transendothelial migration” (Fig. 7b) (adj.p < 0.05). The gene discussed is TBXT; the disease is systemic lupus erythematosus.