[30] found that the interaction of CK2 and its substrate HMGA1 was associated with tyrosine kinase inhibitor resistance for EGFR‐mutant non‐small cell lung cancer and, in addition, HMGA1 and HMGA2 were found to have a very similar structure that includes three conserved domains [31], which supports our results indirectly. Here, EGFR is linked to lung cancer.