VTN and colonic neoplasm: Herein, we observed that CXCL2 stimulation of CT-26 cells increased adhesion of colon cancer cells to vitronectin, fibronectin, collagen IV, laminin I and fibrinogen but not to collagen I. These findings were partially recapitulated in human cells showing that CXCL8 increased HT-29 cell adhesion to fibronectin and laminin I. Notably, flow cytometry revealed that both murine and human colon cancer cells express the αV and β3 integrin subunits.