Considering that the laminin sequence YIGSR and the fibronectin amino acid sequence RGDS have been shown to attenuate peritoneal dissemination of gastric and ovarian cancer cells, respectively [44, 45], future studies should examine if ligands of the αV integrins could be useful to target colon cancer cell spread in the peritoneal cavity. This evidence concerns the gene FN1 and colonic neoplasm.