Glioma patients of the subtype expressing high levels of LEP had a lower fraction of naïve B cells, plasma cells, NK activated cells, and monocytes cells than did those of subtype expressing low levels of LEP, while the opposite was the case for CD4 memory resting T cells and M0 macrophages (P < 0.05, Figure 7B), in accord with the results grouped by the risk score. The gene discussed is CD4; the disease is central nervous system cancer.