IL20RA and cancer: However, we observed a significant increase in the proportion of M1-like (MHCII+ CD206-) macrophages and a dramatic decrease of M2-like (MHCII- CD206+) macrophages in the malignant ascites caused by IL20RA-reconstituted ID8 cells (Figure 3A, B), which were further confirmed by dramatically increased M1-like marker genes and decreased M2-like markers (Figure 3C).