IL-20 and IL-26 were discovered to promote proliferation and migration of bladder cancer, breast cancer, and gastric cancer cells, while IL-24 was found to inhibit the proliferation and metastasis of melanoma, prostate cancer, and OC (Fisher et al., 2007; Gopalan et al., 2007; Hsu et al., 2012; Lee et al., 2013; Pradhan et al., 2018; You et al., 2013). The gene discussed is IL20; the disease is urinary bladder cancer.