IL1B and neoplasm: Research has shown that during the growth and spread of tumors, pro‐inflammatory cytokines such as IL‐1, IFN‐γ, and TNF‐α induce chemokines that attract neutrophils which are key factors in the generation of reactive oxygen species and carcinogenesis.[46] Relevant to such research, elevated levels of pro‐inflammatory cytokines (IL‐6, IL‐1β, and TNF‐α) are observed in mouse models of Parkinson's disease.[66] Additionally, pro‐inflammatory cytokines induce adhesion molecules and metalloproteinases which permit specific mechanisms for tumor invasion.