α-Synuclein BAC transgenic mice show oligomeric forms of α-synuclein in the regions that are specifically affected in LBD, including the olfactory bulb, cerebral cortex, striatum and SNc, and exhibit non-motor symptoms, such as rapid eye movement sleep behavior disorder-like behavior and hyposmia (Taguchi et al. 2020). Here, SNCA is linked to REM sleep behavior disorder.