KDR and leukemia: Several drugs can induce AP: all-trans retinoic acids, cytarabine, and L-asparaginase used to treat leukemia, vascular endothelial growth factor receptor (VEGFR) and tyrosine kinase inhibitors, ICIs and drugs like gemcitabine and capecitabine, which are commonly used in PDAC treatment [10, 57].