Three single nucleotide polymorphisms (SNPs) located in the SRP54 antisense gene were found to be associated with cardiovascular diseases in patients with systemic lupus erythematosus but not with rheumatoid arthritis (Leonard et al., 2018), however, further studies are necessary to clarify the risk of cardiac involvement in SRP-myopathy. The gene discussed is UCN2; the disease is rheumatoid arthritis.