Autosomal-dominant mutations in SRP72 were identified in the pathophysiology of aplastic anemia (AA) and myelodysplasia (MDS), two forms of bone marrow failure that are associated with an increased risk of hematologic malignancy (Kirwan et al., 2012; Galaverna et al., 2018). This evidence concerns the gene SRP72 and Bone marrow hypocellularity.