SRP9 mRNA was found up-regulated in hepatocellular carcinoma via gene array studies (Liu et al., 2007) while a proteomic analysis has shown it was overexpressed in patients with colorectal adenocarcinoma (Rho et al., 2008), suggesting SRP9 as a candidate biomarker for colon cancers. Here, SRP9 is linked to malignant colon neoplasm.