It turned out that the expression of EPCAM (P = 2.31E-02) was positively, while ICAM1 (P = 8.02E-05), THY1 (P = 1.95E-04), and CXCR4 (P = 6.38E-05) were negatively correlated to the tumor purity (Figure 5A), suggesting the expression of EPCAM might be mainly from cancer cells, while the latter three genes might be from the cells in the TME. The gene discussed is ICAM1; the disease is cancer.