It turned out that the expression of EPCAM (P = 2.31E-02) was positively, while ICAM1 (P = 8.02E-05), THY1 (P = 1.95E-04), and CXCR4 (P = 6.38E-05) were negatively correlated to the tumor purity (Figure 5A), suggesting the expression of EPCAM might be mainly from cancer cells, while the latter three genes might be from the cells in the TME. This evidence concerns the gene CXCR4 and cancer.