IL18 and cryptosporidiosis: IL-18, a product of the inflammasome complex, is elevated in human epithelial cell lines following C. parvum infection (McDonald et al., 2006); moreover, IL-18 knockout and inflammasome components caspase-1 or ASC knockout mice are more susceptible to Cryptosporidium infection than control mice (Ehigiator et al., 2005; McNair et al., 2018; Sateriale et al., 2021).