Regarding lung cancer, we explored the datasets of the TCGA-LUSC (n=501) and TCGA-LUAD (n=515) and found a correlation between the high expression of TWF1 and late clinical staging (P<0.01) poor OS prognosis (P<0.001), poor DFS (P<0.01) specific for LUAD but not for LUSC. The gene discussed is TWF1; the disease is lung carcinoma.