TPM2 and cancer: Figure 6, shows the results of the survival analysis with survival curves for TPM2 in six cancer datasets. Similarly, TPM2 has been demonstrated in previous experiments to be a diagnostic marker for colorectal cancer and breast cancer. For example, hypoxia-induced TPM2 methylation is associated with chemoresistance and poor prognoses for breast cancer (21), and is also associated between epigenetic silencing of TPM2 and colorectal cancer (22).