SLC2A4 and diabetes mellitus: Separately, multiple studies have demonstrated the capacity of exercise interventions (of varying design and duration) to induce increases in skeletal muscle and adipose tissue GLUT4 protein expression in human diabetics, alongside improved glycaemic control (Dela et al., 1994; Holten et al., 2004; O’Gorman et al., 2006; Hussey et al., 2011; Little et al., 2011).