Figure 1C demonstrates the AQP4 expression patterns in various brain cancer data available on the CPTAC dataset. Using the TCGA data, we also cohorted patients into having either low- or high-expression groups and investigated the association of AQP4 with patient prognosis. Higher AQP4 expressions were related to poorer patient prognosis as well as shorter OS (Survival) for LGG cancers within the TCGA project (Figure 1D). Here, AQP4 is linked to brain cancer.