Jin et al. (2018) reported that CD70 expression is upregulated on GBM cells following irradiation and that this enhanced CD70-specific CAR T cell mediated tumor cell elimination. Similarly Weiss et al. (2018b) reported increased immune cell infiltration and activity of CAR T cells when combining radiotherapy and NKG2D CAR T cells in murine GBM models. The gene discussed is CD70; the disease is glioblastoma.