PROS1 and COVID-19: For example, mycophenolic acids, broad-spectrum antiviral drugs inhibit the synthesis of nucleosides,63 lopinavir, 3C-like protease (3CLpro) inhibitor, decreases viral replication,64 peptides and monoclonal antibodies target viral dendritic proteins.60,65,66 Controlling the inflammatory response may be as important as inhibiting the viral proliferation and thus another strategy is to target host cell.2,12,67,68 Rational design of antiviral drug combo is a potential strategy for treating COVID-19, but it lacks solid clinical evidence.