TARDBP and amyotrophic lateral sclerosis: A FUS-ALS (FusΔNLS/+)7 and TDP43-ALS (TDP43Q331K/Q331K)34 showed reduction in the number of motor endplates in the gastrocnemius compared to WT littermates at 1 and 10 months, and at 10–12 months of age, respectively.