The cell type specificity of this receptor was confirmed by RT-qPCR analysis of cell populations sorted from dissociated mouse mammary tumours, demonstrating that Mrc2 (Endo180) expression is restricted to the PDGFRα-positive CAF population with no detectable expression on macrophages or other immune cells, endothelial cells, or tumour cells (Fig. 1b and Supplementary Fig. 1b). Here, PDGFRA is linked to neoplasm.