The database included 428 “toxic” sequences (i.e. LCs responsible for the formation of toxic aggregates an AL development) extracted from AL patients (hereafter referred to as tox) and 647 “non-toxic” LCs (nox) comprising sequences from healthy donor repertoires, other autoimmune diseases or cancer, obtained from Amyloid Light-chain Database (AL-Base)21 (428 tox, 590 nox) and an in-house LCs’ database not related to AL (57 nox). This evidence concerns the gene TNFSF14 and axial length measurement.