Notably, similar to that for the B16-OVA tumor model, direct challenge of Maoa WT and KO mice with MC38 tumor cells also resulted in a significantly suppressed tumor growth in Maoa KO mice, confirming a general impact of MAO-A-deficiency on tumor growth for multiple tumor models (Fig. 1b–d and Supplementary Fig. 5l–n). The gene discussed is MAOA; the disease is neoplasm.