These data are concordant with a previous study showing that Δ133p53α triggers proinflammatory cytokine response, including interleukin 6 (IL-6), IL-1β and IL-8 (via inhibition of p53 and induction of NF-κB) in a Helicobacter pylori infection model or cancer model.40 41. The gene discussed is CXCL8; the disease is cancer.