Here, we show that after encountering target tumor cells, the percent of TIGIT-expressing T cells increases to similar levels in control and Δ133p53α-transduced cells, however, the expression level of TIGIT per cell (as determined by MFI values) remained reduced in Δ133p53α-T cells as compared with control cells (700 vs 950) (figure 4E). This evidence concerns the gene TIGIT and neoplasm.