Donizetti-Oliveira et al. [117] conducted a study in a mouse model induced by ischemia reperfusion injury (IRI), and treatment with allogeneic AMSCs reduced IL-1α, IL-6, TNF-α, IL-4, IL-12, RANTES, FSP-1, Col-I, and Hypoxyprobe and inhibited renal fibrosis. Here, S100A4 is linked to renal fibrosis.