Sun et al. [123] injected AF-MSCs via the tail vein in a UUO mouse model and showed that AF-MSCs decreased HIF-1α, TGF-β1, Col-I, MCP-1, Ki67, apoptosis, and renal fibrosis and increased VEGF, E-cadherin, and PCNA. The gene discussed is HIF1A; the disease is renal fibrosis.