PDLIM7 and lip and oral cavity carcinoma: Moreover, we recently pointed out that interaction of high-risk HPVs and EBV oncoproteins (E6/E7, LMP1 and EBNA1) can play an important role in the initiation and/or progression of human breast and oral carcinomas via the epithelial-mesenchymal transition (EMT) event [13, 73], which suggests an analogous mechanism in the pathogenesis of human breast malignancy.