In particular, one region on chromosome 6 (BP 32,583,653 – 32,590,501) in Table 1 was very close to the gene unit (HLA-DRB6; BP: 32,520,489 – 32,527,779) and was identified by colocalization analysis between mQTL and GWAS phase 1 results, indicating shared causal genetic variants within the region that regulate both DNA methylation and CHD risk. The gene discussed is HLA-DRB6; the disease is coronary artery disorder.