However, in contrast to finding with high-risk HPV16 E6 + EBV LMP-1 (16E6 + LMP-1), low-risk HPV6 E6 + EBV LMP-1 (6E6 + LMP-1) did not induce anchorage-independent growth, invasiveness and tumor formation in nude mice. This evidence concerns the gene PDLIM7 and neoplasm.