[26] showed that HOTTIP levels can also be detected in EV purified from bronquioalveolar lavage from NSCLC patients, which indicates that the analysis of HOTTIP levels in this type of samples could also have utility for diagnosis or prognosis analysis in NSCLC patients, but the authors not analyzed specifically the utility of HOTTIP as biomarker is this medium. This evidence concerns the gene HOTTIP and non-small cell lung carcinoma.