FOXO3 and cystic fibrosis: We identify the target of one such peptide probe, 9J10, as the 14-3-3 protein family, which are known mediators of FOXO3a localization and implicated in a wide range of human diseases including cancer, neurodegeneration, and cystic fibrosis (Kaplan et al., 2017; Stevers et al., 2016; Wilker and Yaffe, 2004).