DNMT1 and Huntington disease: Besides the effects of mHTT on transcription factors, previous publications indicated that the dysregulation of epigenetic modifiers such as DNMT1 or histone deacetylases (HDACs) (Federspiel et al, 2019; Siebzehnrübl et al, 2018; Moreno et al, 2016) might contribute to the broad transcriptional dysregulation in HD.