2013). However, flow cytometry using FITC-conjugated Annexin V revealed that GSE exposure did not induce apoptosis of cancer cells (Figure 7(A)). Meanwhile, GSE treatment did not change the expression of apoptosis-related protein, cleaved-caspase-3 (Figure 7(C)). In addition, GSE treatment did not cause nucleic condensation or fragmentation in HepG2 cells (Figure 7(B)). Here, CASP3 is linked to cancer.