1997). IgA is the most abundant Igs in humans and the first line of specific immunological defence against environmental antigens (Reyna-Garfias et al. 2010). Compared with the control group, the level of serum IgA in the IBD mouse decreased (Gong et al. 2019), which is in agreement with our study. The gene discussed is CD79A; the disease is inflammatory bowel disease.