In a meta‐analysis performed by Jelleyman et al. (2015), the authors identified a significant reduction in insulin resistance following HIIT (standardized mean difference of −0.33 95%CI [−0.47 ‐ −0.18]), although these data are not exclusively from studies investigating samples of participants living with obesity and SIT (Jelleyman et al., 2015). The gene discussed is INS; the disease is obesity disorder.