INS and obesity due to melanocortin 4 receptor deficiency: This is concerning as the literature suggests the combination of obesity and metabolic inflexibility (e.g., low fat oxidation at rest or during low‐intensity exercise) increase the likelihood of exhibiting a reduced insulin sensitivity; and thus, increasing the risk of developing Type 2 diabetes mellitus (Kelley et al., 1999; Kelley & Simoneau, 1994).