Mutations in six LGMD-causing genes have also been associated with mitochondrial: CAPN3 (R1), DYSF (R2), SGCA (R3), SGCB (R4), SGCG (R5), and SGCD (R6), with possible involvement from more newly identified LGMD genes such as PYROXD1 (LGMD R#, number pending). The gene discussed is SGCB; the disease is limb-girdle muscular dystrophy.