Increased YKL‐40 in many types of tumors is able to facilitate angiogenesis by motivating the migration and rearrangement of vascular endothelial cells [11], while an anti‐YKL‐40‐neutralizing antibody has been identified to have an inhibitory effect on tumor growth and neovascularization [12, 13, 14]. Here, CHI3L1 is linked to neoplasm.