In this study, children with CHD4 mutations presented as CAE, BECTS, and EFS+, similar as several previously reported genes associated with idiopathic epilepsy, such as GABRG2, SCN9A, and GRIN2A,45, 46 suggesting these epileptic syndromes potentially have similar etiologies. The gene discussed is GRIN2A; the disease is epilepsy syndrome.