LC3 was not significantly different between PD patients and controls (mean 70.32 ± 5.12, and 66.30 ± 3.05, respectively) (P = 0.47) (Fig. 3); this was confirmed in the group of PD patients without genetic alterations (mean LC3 particles/cell, 70.06 ± 4.99). This evidence concerns the gene MAP1LC3A and Parkinson disease.