We further explored the clinical significance of KIF18B mRNA expression in pan-cancers and revealed that KIF18B mRNA expressions were higher in advanced pathological stages (III and IV) in ACC, KIRC, KIRP, KICH, LIHC, SKCM, TGCT, ESCA, and STAD, which pointed to KIF18B playing a role in the carcinogenesis and progression of pan-cancer. The gene discussed is KIF18B; the disease is adrenal cortex carcinoma.