BRD7 and neoplasm: In our previous study, we investigated the impact of BRD7 knockout (BRD7–/–) on DSS-induced colitis and found that BRD7 plays an anti-inflammatory role during early acute colitis in mice (Zhao et al., 2017); the results showed that DAI was significantly increased in DSS-induced acute colitis in BRD7–/– mice from 1 to 5 days, consistent with its tumor-suppressive function in carcinogenesis.