Multiple evidences have reported that circ_DOCK1 could facilitate cell proliferation and constrain apoptosis in various cancers, like thyroid cancer, oral squamous cell carcinoma, bladder cancer, and colorectal cancer (Zhang et al., 2017; Wang et al., 2018; Liu P. et al., 2019; Cui and Xue, 2020). This evidence concerns the gene DOCK1 and oral cavity squamous cell carcinoma.