Genomic biomarkers: Epidermal growth factor receptor (EGFR), Anaplastic lymphoma kinase (ALK), (KRAS), ROS proto-oncogene 1, receptor tyrosine kinase (ROS1), HER2, RET proto-oncogene, MET proto-oncogene, BRAF proto-oncogene, BRAF, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), Neurotrophic receptor tyrosine kinase 1 (NTRK1), Fibroblast growth factor receptor (FGFR), Discoidin domain receptor tyrosine kinase 2 (DDR2)Immunotherapy markers in lung cancer: Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), Programmed death-ligand 1 receptor (PD-1). The gene discussed is RET; the disease is lung cancer.