WNT3A and gastric cancer: Before gastric cancer peritoneal metastasis, Wnt3a-containing TDEs induce PMC infiltration into the gastric wall to create PMN in these sites, which in turn promoted subserosal invasions of gastric cancer cells and further dissemination (120). In addition, three miRNAs, namely miR-10b-5p, miR-101-3p, and miR-143-5p, are proposed biomarkers for gastric cancer lymph node, ovarian, and liver metastasis, respectively (121).