These observations contrast the outcomes of other carcinogen-induced tumorigenesis studies that describe an increase in dysplastic changes following teduglutide treatment (13, 14) and instead support conclusions drawn from experimentation utilizing native GLP-2, wherein there were no increases in malignancy following GLP-2 treatment, utilizing AOM, DMH and the genetic model of human intestinal cancer ApcMin/+ mice (15). Here, GCG is linked to intestinal cancer.