Tau pathology has been also associated with dysfunction and degeneration of RGCs in a rat glaucoma model, 3xTg-AD mouse model of AD and m3R tau-Tg mice exhibiting Pick’s Disease pathology (Chiasseu et al., 2016, 2017; Ngolab et al., 2021). The gene discussed is MAPT; the disease is frontotemporal dementia.