Apart from 98 patients with TNBC, we analyzed total 759 patients with primary breast cancer and showed GPNMB overexpression had no prognostic effect in RFS (P = 0.118; Additional file 1: Fig. S1B), LRFS (P = 0.432; Additional file 1: Fig. S1C) and DMFS (P = 0.182; Additional file 1: Fig. S1D) but OS (P = 0.016; Additional file 1: Fig. S1A). This evidence concerns the gene GPNMB and breast carcinoma.