For the strongest correlation, CT83 mRNA expression is positively correlated with the abundance of type 17 T helper cells (Th17) in esophageal carcinoma (ESCA) (Spearman’s correlation coefficient = 0.442, p = 0.0000) and negatively correlated with effector memory CD4 T cells (Tem_CD4) in rectum adenocarcinoma (READ) (Spearman’s correlation coefficient = − 0.413, p = 0.0000). The gene discussed is CT83; the disease is carcinoma of esophagus.