CT83 and neoplasm: Since the expression of cancer/testis antigens is highly restricted in normal adult tissues and widely distributed in tumor tissues38,39, we examined the expression of CT83 in 120 types of normal human tissues (Fig. 3A), 33 types of cancer tissues (Fig. 3B), 1019 cancer cell lines (Fig. 3C), and 18 types of blood cells (Figure S1).